2nd International Conference on Alzheimers, Dementia and Related Neurodegenerative Diseases

To help relieve the signs and symptoms of MS, try to: Get plenty of rest. Exercise . If you have mild to moderate MS, regular exercise can help improve your strength, muscle tone, balance and coordination. Swimming or other water exercises are good options if you're bothered by heat. Other types of mild to moderate exercise recommended for people with MS include walking, stretching, low-impact aerobics, stationary bicycling, yoga and tai chi. Cool down. MS symptoms often worsen when your body temperature rises. Avoiding exposure to heat and using devices such as cooling scarves or vests can be helpful. Eat a balanced diet. Results of small studies suggest that a diet low in saturated fat but high in omega-3 fatty acids, such as those found in olive and fish oils, may be beneficial. But further research is needed. Studies also suggest that vitamin D may have potential benefit for people with MS. Relieve stress . Stress may trigger or worsen your signs and symptoms. Yo...

Beta interferons. These medications are among the most commonly prescribed medications to treat MS. Ocrelizumab (Ocrevus). This humanized immunoglobulin antibody medication is the only DMT approved by the FDA to treat both the relapse-remitting and primary progressive forms of MS. Clinical trials showed it reduced relapse rate in relapsing disease and slowed worsening of disability in both forms of the disease. Glatiramer acetate (Copaxone). This medication may help block your immune system's attack on myelin and must be injected beneath the skin. Side effects may include skin irritation at the injection site. Dimethyl fumarate (Tecfidera). This twice-daily oral medication can reduce relapses. Side effects may include flushing, diarrhea , nausea and lowered white blood cell count. Fingolimod (Gilenya). This once-daily oral medication reduces relapse rate. Teriflunomide (Aubagio). This once-daily medication can reduce relapse rate. Teriflunomide can cause liver damage, h...

Corticosteroids , such as oral prednisone and intravenous methylprednisolone, are prescribed to reduce nerve inflammation. Side effects may include insomnia, increased blood pressure, mood swings and fluid retention. Plasmaexchange (plasmapheresis) . The liquid portion of part of your blood (plasma) is removed and separated from your blood cells. The blood cells are then mixed with a protein solution (albumin) and put back into your body. Plasma exchange may be used if your symptoms are new, severe and haven't responded to steroids. Treatments for MS signs and symptoms Physical Therapy. A physical or occupational therapist can teach you stretching and strengthening exercises and show you how to use devices to make it easier to perform daily tasks. Physical therapy along with the use of a mobility aid when necessary can also help manage leg weakness and other gait problems often associated with MS. Muscle Relaxants. You may experience painful or uncontrollable muscle...

There are no specific tests for MS. Instead, a diagnosis of multiple sclerosis often relies on ruling out other conditions that might produce similar signs and symptoms, known as a differential diagnosis. Doctor is likely to start with a thorough medical history and examination. These tests may be recommended by doctor: Blood Tests , to help rule out other diseases with symptoms similar to MS. Tests to check for specific bio-markers associated with MS are currently under development and may also aid in diagnosing the disease. Lumbar Puncture (Spinal Tap), in which a small sample of fluid is removed from your spinal canal for laboratory analysis. This sample can show abnormalities in antibodies that are associated with MS. Spinal tap can also help rule out infections and other conditions with symptoms similar to MS. MRI, which can reveal areas of MS (lesions) on your brain and spinal cord. You may receive an intravenous injection of a contrast material to highlight le...

Because the effects of nerve injury are widespread, the many complications can be very severe and affect all parts of the body. Although not all individuals with multiple sclerosis (MS) experience all of the following complications, any of them can negatively affect the individual's quality of life. Fatigue: Fatigue is one of the most common and debilitating MS symptoms and affects at least two thirds of patients with MS. Fatigue causes a general lack of energy that significantly limits daily functioning regardless of any neurologic symptoms or specific muscle weaknesses. Loss of mobility and spasticity: Nearly every individual with MS loses some mobility, which may take the form of impaired motor control, muscle weakness, impaired balance, tremor, and, importantly, spasticity. Spasticity is one of the primary symptoms of MS. Pain: About two-thirds of MS patients experience pain at some point during the course of the disease and 40% are never pain free. Bowel dysfunctio...

These factors may increase your risk of developing multiple sclerosis: Age. Multiple Sclerosis can occur at any age, but most commonly affects people between the ages of 15 and 60. Sex. Women are about twice as likely as men are to develop MS. Family history. If one of your parents or siblings has had MS, you are at higher risk of developing the disease . Certain infections. A variety of viruses have been linked to MS, including Epstein-Barr, the virus that causes infectious mononucleosis. Race. White people, particularly those of Northern European descent, are at highest risk of developing MS. People of Asian, African or Native American descent have the lowest risk. Climate. MS is far more common in countries with temperate climates, including Canada, the northern United States, New Zealand, southeastern Australia and Europe. Certain autoimmune diseases. You have a slightly higher risk of developing MS if you have thyroid disease, type 1 diabetes or inflammatory b...

The cause of multiple sclerosis is unknown. It's considered an autoimmune disease in which the body's immune system attacks its own tissues. In the case of MS, this immune system malfunction destroys myelin (the fatty substance that coats and protects nerve fibers in the brain and spinalcord ). Myelin can be compared to the insulation coating on electrical wires. When the protective myelin is damaged and nerve fiber is exposed, the messages that travel along that nerve may be slowed or blocked. The nerve may also become damaged itself. It isn't clear why MS develops in some people and not others. A combination of genetics and environmental factors appears to be responsible. To know more about Multiple Sclerosis Join us at the International Conference on #Alzheimers, # Dementia and Related #Neurodegenerative Diseases at https://bit.ly/2HlLuhx

Most people with Multiple Sclerosis have a relapsing-remitting disease course. They experience periods of new symptoms or relapses that develop over days or weeks and usually improve partially or completely. These relapses are followed by quiet periods of disease remission that can last months or even years. Small increases in body temperature can temporarily worsen signs and symptoms of MS, but these aren't considered disease relapses. About 60 to 70 percent of people with relapsing-remitting MS eventually develop a steady progression of symptoms, with or without periods of remission, known as secondary-progressive MS . The worsening of symptoms usually includes problems with mobility and gait. The rate of disease progression varies greatly among people with secondary-progressive MS. Some people with MS experience a gradual onset and steady progression of signs and symptoms without any relapses. This is known as primary-progressive MS . Multiple Sclerosis ...

Multiple sclerosis signs and symptoms may differ greatly from person to person and over the course of the disease depending on the location of affected nerve fibers. They may include: Numbness or weakness in one or more limbs that typically occurs on one side of your body at a time, or the legs and trunk Partial or complete loss of vision, usually in one eye at a time, often with pain during eye movement Prolonged double vision Tingling or pain in parts of your body Electric-shock sensations that occur with certain neck movements, especially bending the neck forward (Lhermitte sign) Tremor, lack of coordination or unsteady gait Slurred speech Fatigue Dizziness Problems with bowel and bladder function To know more about the recent research going on in the field of Multiple Sclerosis, join us at the  International Conference on # Alzheimers , #Dementia and Related #Neurodegenerative Diseases https://bit.ly/2HlLuhx

Multiple sclerosis (MS) is a potentially disabling disease of the brain and spinal cord (central nervous system). In MS, the immune system attacks the protective sheath (myelin) that covers nerve fibers and causes communication problems between your brain and the rest of your body. Eventually, the disease can cause the nerves themselves to deteriorate or become permanently damaged. Signs and symptoms of MS vary widely and depend on the amount of nerve damage and which nerves are affected. Some people with severe MS may lose the ability to walk independently or at all, while others may experience long periods of remission without any new symptoms . There's no cure for multiple sclerosis . However, treatments can help speed recovery from attacks, modify the course of the disease and manage symptoms. International Conference on #Alzheimers, #Dementia and Related #Neurodegenerative Diseases which is scheduled on 27-28 August, 2018 at Madrid, Spain is coming up wit...

If the seizures are related to another medical condition, identification and treatment of that medical condition is the key to prevention. If anticonvulsant medication is prescribed, taking the medication on the recommended schedule and not missing medication is important. Some people with epilepsy are quite sensitive to alcohol. If this pattern develops, avoid alcohol. Others may have seizures only after ceasing heavy alcohol intake. The key to prevention is avoidance of alcohol. Sleep deprivation and stress certainly may increase the frequency of seizures in some people with epilepsy . Epilepsy Outlook Epilepsy simply describes the condition of recurrent seizures. The outcome of the seizure disorder is strongly related to the cause of the seizures, if a cause is discovered. For people with symptomatic epilepsy -that is, seizures that occur because other medical conditions exist -prognosis will depend on the other medical condition. Seizures resulting from low ...

Home care with epilepsy varies with the frequency and type of seizures. It is important to take anticonvulsant medication regularly to prevent seizures. When a seizure occurs, an observer can use common sense to prevent injuries. Cushion the person's head. Loosen any tight neckwear. Turn the person on his or her side. Do not hold the person down or restrain the person. Do not place anything in the mouth or try to pry the teeth apart. The person is not in danger of swallowing his or her tongue. Observe seizure characteristics-length, type of movements , direction of head or eye turning. These characteristics may help the doctor diagnose the type of seizure. To know more about how to deal with Epilepsy... Join us at Madrid, Spain on 27-28 August, 2018 by participating at the  International Conference on #Alzheimers, #Dementia and Related #Neurodegenerative Diseases... Book your slots at  https://bit.ly/2HlLuhx

Epilepsy carries a risk of premature mortality, but little is known about life expectancy in people with the condition.  In 2013, researchers from the University of Oxford and University College London in the U.K. reported that people with epilepsy are 11 times more likely to experience premature death, compared with the rest of the population. The risk appears to be greater if the person also has a mental illness. Suicides, accidents, and assaults accounted for 15.8 percent of early deaths. Most people affected by these had also been diagnosed with a mental disorder . Head researcher, Seena Fazel said: "Our results have significant public health implications, as around 70 million people worldwide have epilepsy, and they emphasize that carefully assessing and treating psychiatric disorders as part of standard checks in persons with epilepsy could help reduce the risk of premature death in these patients. Our study also highlights the importance of suicide and ...

A study published in 2005 suggested that people with severe epilepsy who continue to experience seizures were more likely to have difficulties with cognitive ability and brain function. Longer periods of remission were linked with fewer cognitive problems. A review published in 2006 concluded that there may be a "mild but measurable" decline in some people in intellectual performance" of adults and children. However, the researchers point out that there is little reliable research in this area, and that "Due to many confounding variables, the effect of seizures per se is difficult to estimate, but appears limited." Recent studies have looked at cognitive changes in children as they age, either with or without epilepsy. Results suggest that epilepsy is associated with worse cognitive outcomes. However, it is unclear whether: epilepsy causes the impairment a similar structural change causes both the epilepsy and the impairment anti-...

Seizures are the only symptom of epilepsy. Epilepsy is defined as having "two or more unprovoked seizures," according to Johns Hopkins Medicine. Some people have a single seizure, or seizures that are not linked to epilepsy. According to the United Kingdom's Epilepsy Society, non-epileptic seizures are not due to electrical activity in the brain. The causes can be physical, emotional, or psychological. There are also different types of seizure. Seizures may vary between people with epilepsy, so in two individuals, the condition may look different. For this reason, it can be called a spectrum disorder . Outlook Epilepsy can affect a person's life in multiple ways, and the outlook will depend on various factors. Will seizures continue? If the cause is clearly identifiable, seizures are more likely to continue. Other factors affecting the chances of remission include: access to treatment response to treatment age when symptoms started ...

There is currently no cure for most types of epilepsy . However, surgery can stop some kinds of seizure from occurring, and in many cases, the condition can be managed. If an underlying correctable brain condition is causing the seizures , sometimes surgery can stop them. If epilepsy is diagnosed, the doctor will prescribe seizure-preventing drugs or anti-epileptic drugs. If drugs do not work, the next option could be surgery, a special diet or VNS (vagus nerve stimulation). The doctor's aim is to prevent further seizures from occurring, while at the same time avoiding side effects so that the patient can lead a normal, active, and productive life.  Anti-epileptic drugs (AEDs) The majority of AEDs are taken orally. The type of seizure the patient is having will decide which drug the doctor may prescribe. Patients do not all react in the same way to drugs, but AEDs appear to help control seizures in 70 percent of cases. Drugs commonly used to treat epilepsy ...

There are three descriptions of seizures , depending on where in the brain the activity started. Partial Seizure A partial seizure means the epileptic activity took place in just part of the patient's brain. There are two types of partial seizure: Simple partial seizure - the patient is conscious during the seizure. In most cases, the patient is also aware of their surroundings, even though the seizure is in progress. Complex partial seizure - the patient's consciousness is impaired. The patient will generally not remember the seizure, and if they do, their memory will be vague. Generalized Seizure A generalized seizure occurs when both halves of the brain have epileptic activity. The patient's consciousness is lost while the seizure is in progress. Tonic-clonic seizures (previously known as grand mal seizures): Perhaps the best known type of generalized seizure . They cause a loss of consciousness, body stiffness, and shaking. Absence seiz...

A person with epilepsy will have recurrent seizures. Every function in the human body is triggered by messaging systems in our brain. Epilepsy results when this system is disrupted due to faulty electrical activity. In many cases, the exact cause is not known. Some people have inherited genetic factors that make epilepsy more likely to occur. Other factors that may increase the risk include: head trauma, for instance, during a car crash brain conditions, including stroke or tumors infectious diseases, for instance, AIDS and viral encephalitis prenatal injury, or brain damage that occurs before birth developmental disorders, for instance, autism or neurofibromatosis It is most likely to appear in children under 2 years of age, and adults over 65 years. What a patient with epilepsy experiences during a seizure will depend on which part of the brain is affected, and how widely and quickly it spreads from that area. Join us at the International Confer...

Epilepsy is a neurological condition. The main symptom of epilepsy is repeated seizures. If one or more of the following symptoms are present, the individual should see a doctor, especially if they recur: a convulsion with no temperature (no fever) short spells of blackout, or confused memory intermittent fainting spells, during which bowel or bladder control is lost, which is frequently followed by extreme tiredness for a short period, the person is unresponsive to instructions or questions and becomes stiff the person suddenly falls for no clear reason sudden bouts of blinking and chewing without apparent stimuli and apparent reason for a short time the person seems dazed and unable to communicate the person becomes fearful for no apparent reason; they may even panic or become angry peculiar changes in senses, such as smell, touch, and sound the arms, legs, or body jerk, in babies these will appear as a cluster of rapid jerking movements ...

People with epilepsy experience recurrent seizures , because a sudden surge of electrical activity in the brain causes a temporary disturbance in the messaging systems between brain cells. The Centers for Disease Control and Prevention (CDC) describe epilepsy as "a common neurological condition characterized by recurrent seizures." Here are some key points about epilepsy Epilepsy is a neurological disorder. Primary symptoms commonly include seizures. Seizures have a range of severity depending on the individual. Treatments include anti-seizure medications. To know more about #Epilepsy and other Neurodegenerative Diseases, Join us at the  International Conference on #Alzheimers, #Dementia and Related # Neurodegenerative #Diseases https://bit.ly/2p9olWH 

Alzheimer's disease is currently ranked as the sixth leading cause of death in the United States, but recent estimates indicate that the disorder may rank third, just behind heart disease and cancer, as a cause of death for older people. Alzheimer’s is the most common cause of dementia among older adults. Dementia is the loss of cognitive functioning—thinking, remembering, and reasoning—and behavioral abilities to such an extent that it interferes with a person’s daily life and activities. Dementia ranges in severity from the mildest stage, when it is just beginning to affect a person’s functioning, to the most severe stage, when the person must depend completely on others for basic activities of daily living. The causes of dementia can vary, depending on the types of brain changes that may be taking place. Other dementias include Lewy body dementia , frontotemporal disorders, and vascular dementia. It is common for people to have mixed dementia—a combination of two o...

Research suggests that a host of factors beyond genetics may play a role in the development and course of Alzheimer’s disease . There is a great deal of interest, for example, in the relationship between cognitive decline and vascular conditions such as heart disease, stroke, and high blood pressure, as well as metabolic conditions such as diabetes and obesity. Ongoing research will help us understand whether and how reducing risk factors for these conditions may also reduce the risk of Alzheimer’s. A nutritious diet, physical activity, social engagement, and mentally stimulating pursuits have all been associated with helping people stay healthy as they age. These factors might also help reduce the risk of cognitive decline and Alzheimer’s disease. Clinical trials are testing some of these possibilities. To know more about Alzheimer's Disease and other related Neurodegenerative Diseases, Join us at the International Conference on #Alzheimers, #Dementia and Related # Neu...

Most people with Alzheimer’s have the late-onset form of the disease, in which symptoms become apparent in their mid-60s. The apolipoprotein E (APOE) gene is involved in late-onset Alzheimer’s. This gene has several forms. One of them, APOE ε4, increases a person’s risk of developing the disease and is also associated with an earlier age of disease onset. However, carrying the APOE ε4 form of the gene does not mean that a person will definitely develop Alzheimer’s disease, and some people with no APOE ε4 may also develop the disease. Also, scientists have identified a number of regions of interest in the genome (an organism's complete set of DNA ) that may increase a person's risk for late-onset Alzheimer's to varying degrees. Early-onset Alzheimer’s disease occurs between a person’s 30s to mid-60s and represents less than 10 percent of all people with Alzheimer’s. Some cases are caused by an inherited change in one of three genes, resulting in a type known as e...

Two abnormal structures called plaques and tangles are prime suspects in damaging and killing nerve cells. Plaques are deposits of a protein fragment called beta-amyloid that build up in the spaces between nerve cells. Tangles are twisted fibers of another protein called tau that build up inside cells. Though autopsy studies show that most people develop some plaques and tangles as they age, those with Alzheimer’s tend to develop far more and in a predictable pattern, beginning in the areas important for memory before spreading to other regions. Scientists do not know exactly what role plaques and tangles play in Alzheimer's disease. Most experts believe they somehow play a critical role in blocking communication among nerve cells and disrupting processes that cells need to survive. It's the destruction and death of nerve cells that causes memory failure, personality changes, problems carrying out daily activities and other symptoms of Alzheimer's...