'More potent' Alzheimer's therapy is on its way

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Alzheimer's disease is characterized by the formation of amyloid plaques in the brain, which interfere with the normal communication flow between brain cells. These plaques are made out of beta-amyloid amino acids that stick together.

Over the past few years, researchers from various institutions have been working to develop antibodies - a type of protein harnessed by the immune system as part of the immune response able to interfere with beta-amyloid and prevent the formation of plaques in the brain.

But the search for effective antibodies, though promising, has been riddled with obstacles and setbacks. That is why a team of researchers from Brigham and Women's Hospital in Boston, MA, has recently conducted a series of experiments to identify a better way of targeting beta-amyloid.

This, they hoped, would lead to the development of a more efficient antibody to be used in Alzheimer's therapy.

Principal investigator Dominic Walsh and team came up with a novel technique to collect beta-amyloid and to prepare it in the laboratory.

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