The brain may clean out Alzheimer’s plaques during sleep
Losing Sleep
One Bad Night
To know more join us at #Alzheimers2018 at Madrid, Spain on December 03-04, 2018.
Alzheimer’s disease disrupts sleep. And disrupted sleep
itself might encourage Alzheimer’s by allowing build-up of amyloid-beta, or
A-beta, which is thought to lead to the death of neurons. This cycle of sleep
deprivation can also affect levels of the hormone melatonin, which helps the
body to sleep, and can interfere with metabolism, a disruption that is also a
risk factor for Alzheimer’s.
One Bad Night
Using PET scans to measure amyloid-beta markers, researchers
compared levels of A-beta in the brains of 20 healthy volunteers after one
restful night and after one night of sleep deprivation. Levels of the
plaque-forming A-beta rose in most people tested.
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