Prion Disease: Overview

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Prion diseases or transmissible spongiform encephalopathies (TSEs) are a family of rare progressive neurodegenerative disorders that affect both humans and animals. They are distinguished by long incubation periods, characteristic spongiform changes associated with neuronal loss, and a failure to induce inflammatory response.

The causative agents of TSEs are believed to be prions. The term “prions” refers to abnormal, pathogenic agents that are transmissible and are able to induce abnormal folding of specific normal cellular proteins called prion proteins that are found most abundantly in the brain. The functions of these normal prion proteins are still not completely understood. The abnormal folding of the prion proteins leads to brain damage and the characteristic signs and symptoms of the disease. Prion diseases are usually rapidly progressive and always fatal.

Identified Prion Diseases

Listed below are the prion diseases identified to date. CDC does not currently offer information on every prion disease listed below.

Human Prion Diseases
  • Creutzfeldt-Jakob Disease (CJD)
  • Variant Creutzfeldt-Jakob Disease (vCJD)
  • Gerstmann-Straussler-Scheinker Syndrome
  • Fatal Familial Insomnia
  • Kuru
Animal Prion Diseases
  • Bovine Spongiform Encephalopathy (BSE)
  • Chronic Wasting Disease (CWD)
  • Scrapie
  • Transmissible mink encephalopathy
  • Feline spongiform encephalopathy
  • Ungulate spongiform encephalopathy
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Comments

  1. Finlay Cedar27 May 2019 at 04:38

    My husband has been diagnosed with Alzheimer in 2016 there's a herbal foundation in Johannesburg they cured my husband  Alzheimer's disease . Pm me i will give their details. People can search about them on Google or youtube(total cure herbal foundation). My husband faced many difficulties and was in several depression, Trouble understanding visual image, aggression ,so many,. This thing happened to him in very crucial stage of our life. PM if someone needs info or buy direct from them totalcureherbsfoundation.com they cured 100% of Alzheimer with their herbal formula .

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  2. Jerry Atson23 December 2019 at 23:00

    My sister was diagnosed of Creutzfeldt–Jakob disease (CJD) in early last year , our doctor told us there is no permanent cure for the CJD condition, she was given medications to slow down the progress of the disease, at the initial stage it was not so bad till it progressed to the end stage were she had difficulties going about her daily functions as she constantly had difficulty speaking,mental confusion,blurred vision include, we were all totally devastated not until my daughter’s co-worker told us about a herbal formula from totalcureherbsfoundation .com which has the right herbal formula for my sister Creutzfeldt–Jakob disease , when I contact this herbal foundation through their email totalcureherbalfoundation@ gmail. com I wasn’t certain the herbal treatment will get rid of herbal disease not until she complete the treatment as instructed, she will be resuming her work next month because this herbal cure seriously reverse her condition which we never expected ,im referring this to anybody at there suffering from this condition and they have assurance about this treatments

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